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李晓伟     特聘研究员,博士生导师

研究方向:有机超分子功能材料;生物纳米技术

联系方式:028-85418755          Email:lixw@scu.edu.cn

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简历:

学习及工作经历

2021.12-至今 bwin必赢,特聘研究员,博士生导师

2017.09-2020.11 美国爱荷华州立大学,化学系,博士后,导师:Yan Zhao 教授

2012.09-2017.06 四川大学,bwin必赢,硕博连读,博士,导师:袁立华 教授

2008.09-2012.06 四川大学,bwin必赢,本科,导师:袁立华 教授

学术兼职

Chinese Chemical Letters(中国化学快报)第四届青年编委会委员

研究方向

课题组研究方向以有机合成化学为基础,以新型超分子大环、金属/有机分子笼、机械互锁多孔聚合物等功能分子或材料为研究工具,聚焦超分子化学、催化科学以及纳米生物技术等前沿交叉研究领域,探索其在精准识别、拟酶催化及吸附分离等方面的功能应用。

课题组诚招研究助理、博/硕士研究生以及联合培养学生,同时欢迎对超分子化学和有机功能材料感兴趣的本科生进组参与科研项目和毕业论文设计

主要工作业绩

分子识别是一切生命活动的基础,设计构建具有仿生识别功能的超分子主体和功能材料在环境科学、功能材料、生物医药及生命健康等重要领域产生重要且广泛的潜在应用价值。课题组以“超分子组装与精准分子识别调控的高效催化”为核心研究理念,设计开发超分子功能系统应用于模拟酶催化、高效吸附分离以及精准分子识别等实际应用。截至目前发表论文20余篇,以第一或通讯作者在J. Am. Chem. Soc.3篇)、Angew. Chem. Int. Ed. 3篇)、Chem. Sci. 2篇)、ACS Catal.Green Chem.Chem. Commun.Chem. Eur. J.等期刊,部分工作被选为期刊封面或被科技媒体转载亮点评述。此外,课题组已有多名本科生作为共同作者参与发表SCI论文,并保送进入国内外知名学府深造。

主要奖励和荣誉

2023 四川大学优秀班主任

2023年入选四川省天府峨眉计划青年项目

2022年四川大学优秀科研人才奖

2022年入选国家海外高层次人才引进计划青年项目

2021年入选四川大学双百B计划人才项目;

主要代表性论文

入职工作后:

1. Zhiyao Yang, Xirui Wang, Emanuele Penocchio,* Giulio Ragazzon,* Xinnan Chen (本科生), Shuai Lu, Yidan Zhou, Kuirong Fu, Zejiang Liu, Yinmin Cai, Xiujun Yu,* Xiaopeng Li, Xiaowei Li,* Wen Feng, Lihua Yuan* Beyond Single-Cycle Autonomous Molecular Machines: Light-Powered Shuttling in a Multi-Cycle Reaction Network. Angew. Chem., Int. Ed. 2024, e202414072.

2. Song Huang, Zhenwen Wang, Jinyang Wu, Xinyan Mai (本科生), Song Qin, Yuqiao Zhou, Daqiang Yuan, Xiaowei Li,* Wen Feng and Lihua Yuan* A Molecular Sheaf: Doubly Threaded [6]Rotaxane. Chem. Commun. 2024, 60, 5622-5625.

3. Song Huang, Xiaowei Li,* Yimin Cai, Wen Feng, and Lihua Yuan* Construction of Oligorotaxanes with Hydrogen-Bonded Aramide Macrocycles through Threaded Host-Guest Complexation. Chem. Eur. J. 2024, e202303394. (Invited Concept)

4. Yidan Zhou, Zejiang Liu, Zhiyao Yang, Yuexuan Zheng (本科生), Maoxia Yang, Wen Feng, Xiaowei Li* and Lihua Yuan* Pillar[5]arene-segregated ion pairs for enhanced cycloaddition of epoxides with CO2. Chem. Commun. 2024, 60, 300-303.

5. Hui Liu, Pengcheng Wu, Ke Wang, Qing Li, Chengkan Yu, Xiaowei Li, Yimin Cai,* Wen Feng.*, Lihua Yuan* Palladium recovery from acidic solution with phenanthroline-based covalent organic polymers as adsorbents for efficient heterogeneous catalysis. Green. Chem. 2024, 26, 804-814.

6. Zhenwen Wang, Lei Mei, Chenxing Guo, Song Huang, Wei-Qun Shi, Xiaowei Li, Wen Feng, Xiaopeng Li,* Cheng Yang,* and Lihua Yuan* Supramolecular Shish Kebabs: Higher Order Dimeric Structures from Ring-in-Rings Complexes with Conformational Adaptivity. Angew. Chem., Int. Ed. 2023, e202216690.

7. Jinyang Wu, Youran Luo, Lingxuan Chen, Xuan Sun (本科生), Xinnan Chen (本科生), Song Qin, Wen Feng,* Xiaowei Li,* and Lihua Yuan* A Host-Guest Interaction Activated Bobbitt Oxidant for Highly Efficient Oxidation of Alcohols. Chem. Commun. 2022, 58, 12867-12870.

8. Yidan Zhou, Jinyang Wu, Zejiang Liu, Weitao Xu, Menglong Liu, Along Jia (本科生), Yuchen Liu, Xiao Xin, Xiaowei Li,* Lihua Yuan* Threading of Three Rings on Two Stations: a Convergent Approach to [4]Rotaxane. Chem. Commun. 2021, 13506-13509. (Cover paper)

9. Jinyang Wu, Xuan Sun (本科生), Xianghui Li, Xiaowei Li, Wen Feng, Lihua Yuan* Multi-Responsive Molecular Encapsulation and Release Based on Hydrogen-Bonded Azo-Macrocycle. Molecules. 2023, 28, 4437.

10. Jinyang Wu, Long Chen, Xuan Sun (本科生), Song Huang, Xiaowei Li, Wen Feng and Lihua Yuan* Controlling Selective Formation of [2]- and [3]pseudorotaxanes by Tuning Chain Length of Guests. Supramol. Chem. 2023, doi.org/10.1080/10610278.2023.2223333.

11. Xiaowei Li, Yan Zhao* Environmental Modulation of Chiral Prolinamide Catalysts for Stereodivergent Conjugate Addition. J. Catal. 2022, 406, 126-133.

 

入职工作前:

12. Xiaowei Li, Milad Zangiabadi, Yan Zhao* Molecularly Imprinted Synthetic Glucosidase for the Hydrolysis of Cellulose in Aqueous and Nonaqueous Solutions. J. Am. Chem. Soc. 2021, 143, 5172-5181.

13. Xiaowei Li, Kaiqian Chen, Yan Zhao* Sequence-Selective Protection of Peptides from Proteolysis. Angew. Chem., Int. Ed. 2021, 60, 11092-11097. (Frontispiece, Hot paper)

14. Xiaowei Li, Tania M. Palhano Zanela, Eric S. Underbakke, Yan Zhao* Controlling Kinase Activities by Selective Inhibition of Peptide Substrates. J. Am. Chem. Soc. 2021, 143, 639-643.

15. Xiaowei Li, Yan Zhao* Synthetic Glycosidase for Precise Hydrolysis of Oligosaccharides and Polysaccharides. Chem. Sci. 2021, 12, 374-383.

16. Xiaowei Li, Yan Zhao* Synthetic Glycosidase Distinguishing Glycan and Glycosidic Linkage in Its Catalytic Hydrolysis. ACS Catal. 2020, 10, 13800-13808.

17. Xiaowei Li, Yan Zhao* Chiral Gating for Size- and Shape-Selective Asymmetric Catalysis. J. Am. Chem. Soc. 2019, 141, 13749-13752. (Selected as supplementary cover, highlighted in Chemistry Views, X-mol).

18. Xiaowei Li, Xiangyang Yuan, Pengchi Deng, Lixi Chen, Yi Ren, Chengyuan Wang, Lixin Wu, Wen Feng, Bing Gong and Lihua Yuan* Macrocyclic Shape-Persistency of Cyclo[6]aramide Results in Enhanced Multipoint Recognition for Highly Efficient Template-Directed Synthesis of Rotaxanes. Chem. Sci. 2017, 8, 2091-2100.

19. Xiaowei Li, Bao Li, Long Chen, Jinchuan Hu, Chengdanyang Wen, Qingdong Zheng, Lixin Wu, Huaqiang Zeng, Bing Gong* and Lihua Yuan* Liquid-Crystalline Mesogens Based on Cyclo[6]aramides: Distinctive Phase Transitions in Response to Macrocyclic Host-Guest Interactions. Angew. Chem., Int. Ed. 2015, 54, 11147-11152.

20. Shanshan Shi, Yumin Zhu, Xiaowei Li, Xiangyang Yuan, Teng Ma, Wen-Li Yuan, Guo-Hong Tao, Wen Feng and Lihua Yuan* Ion-Pair Recognition of Amidinium Salts by Partially Hydrogen-Bonded Heteroditopic Cyclo[6]aramide. RSC Adv. 2016, 6, 39839-39845.

21. Long Chen, Zhiyong Peng, Shuo Liu, Xiaowei Li, Rongzhou Chen, Yi Ren, Wen Feng and Lihua Yuan* “Cyclo[6]aramide-Tropylium Charge Transfer Complex as a Colorimetric Chemosensor for Differentiation of Intimate and Loose Ion Pairs” Org. Lett. 2015, 17, 5950-5953.

22. Youzhou He, Min Xu, Rongzhao Gao, Xiaowei Li, Fengxue Li, Xuedan Wu, Dingguo Xu*, Huaqiang Zeng and Lihua Yuan* “Two-Component Supramolecular Gels Derived from Amphiphilic Shape-Persistent Cyclo[6]aramides for Specific Recognition of Native Arginine” Angew. Chem., Int. Ed. 2014, 53, 11834-11839.

23. Jinchuan Hu, Long Chen, Yi Ren, Pengchi Deng, Xiaowei Li, Youjia Wang, Yiming Jia, Jian Luo, Xinshi Yang, Wen Feng* and Lihua Yuan* “Nonaggregational Shape-Persistent Cyclo[6]aramide and Its Macrocyclic Effect toward Binding Secondary Ammonium Salts in Moderately Polar Media” Org. Lett., 2013, 15, 4670-4673.

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