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罗美明     教 授/博士生导师

研究方向:金属有机化学; 有机合成方法学

联系方式:          Email:luom2@aliyun.com; luomm@hotmail.com

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简历

1982-1986,四川大学化学系有机化学专业,获理学学士学位。

1986-1989,四川大学化学系有机化学专业,获理学硕士学位。

1989-1996,四川大学分析测试中心材料研究所,先后任实习研究员、助理研究员。

1993-1996,四川大学化学系有机化学专业,获理学博士学位。

1996-2000,四川大学化学系,先后任讲师、副教授。

1998-2000,长崎大学药学院,任日本学术振兴会博士后研究员。

2000-现在,bwin必赢教授,2003年被评为博士生导师。

主要研究方向

金属有机化学; 有机合成方法学;药物合成。

主要工作业绩

教学:主编本科有机化学教材四本,其中国家十一五规划教材二本;副主编本科有机化学教材四本,其中国家十一五十三五规划教材各一本;参编本科有机化学教材七本,其中国家十一五十二五规划教材各一本。参编研究生教材一本。主讲有机化学、基础有机化学实验、有机分析实验等本科课程和现代有机合成、高等有机化学实验等研究生课程。负责的有机化学课程被认定为四川省一流本科课程。获四川大学优秀教学成果二等奖、四川大学课堂教学质量优秀奖,指导学生三次获四川大学本科优秀毕业论文。被授予大学生课外科技实践活动优秀指导教师。

科研:开展有机合成方法学、过渡金属络合催化、药物合成等方面的研究工作,承担国家自然科学基金等各类科研项目二十余项,获教育部科技进步二等奖一项、四川省科技进步三等奖一项,获授权中国发明专利十多项。在J. Am. Chem. Soc.Angew. Chem. Int. Ed.Nat. Commun., Chem. Commun., Org. Lett.等国内外著名期刊发表论文一百多篇。

代表性成果(获奖成果、专著、论文、专利)

1. Liang Ling, Chenyang Hu, Linhong Long, Xue Zhang, Lixing Zhao, Liu Leo Liu, Hui Chen,* Meiming Luo,* Xiaoming Zeng,* Chromium-catalyzed stereodivergent E- and Z-selective alkyne hydrogenation controlled by cyclic (alkyl)(amino)carbene ligands, Nat. Commun. 2023, 14, 990.

2. Haohao Zeng, Shangru Yang, Chao Li, Fei Fan, Liang Ling, Meiming Luo,* Xiaoming Zeng,* Chromium-catalyzed couplings of C(aryl)–SMe bonds in accessing arylated and alkylated benzaldehyde derivatives, Chem. Commun. 202258, 7094–7097.

3. Jinghua Tang, Liang Ling, Shuqing Yuan, Meiming Luo,* Xiaoming Zeng,* Catalytic Cleavage of Unactivated C(aryl)−P Bonds by Chromium, Org. Lett. 202224, 1581−1586.

4. Fei Fan, Lixing Zhao, Meiming Luo,* Xiaoming Zeng,* Chromium-Catalyzed Selective Cross-Electrophile Coupling between Unactivated C(aryl)–F and C(aryl)–O Bonds, Organometallics 202241, 561−568. 

5. Junyao Xie, Xiaoming Zeng, Meiming Luo,* Ni-Catalysed Regioselective α,β-Diarylation of α,β-Unsaturated Aldehydes, Acta Chim. Sinica 202179, 1118–1122.

6. Aiping Fu, Lixing Zhao, Chao Li, Meiming Luo, Xiaoming Zeng,* Chromium-Catalyzed Borylative Coupling of Aliphatic Bromides with Pinacolborane by Hydrogen Evolution, Organometallics 202140, 2204−2208.

7. Shuqing Yuan, Liang Ling, Jinghua Tang, Meiming Luo,* Xiaoming Zeng,* Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C–O Bonds, Synthesis 202153, 3343–3350.

8. Changpeng Chen, Liang Ling, Meiming Luo, Xiaoming Zeng,* Chromium-Catalyzed Ligand-Free Amidation of Esters with Anilines, Bull. Chem. Soc. Jpn. 202194, 762–766.

9. Lixing Zhao, Chenyang Hu, Xuefeng Cong, Gongda Deng, Liu Leo Liu, Meiming Luo, Xiaoming Zeng,* Cyclic (Alkyl)(amino)carbene Ligand-Promoted Nitro Deoxygenative Hydroboration with Chromium Catalysis: Scope, Mechanism, and Applications, J. Am. Chem. Soc. 2021, 143, 1618−1629.

10. Jinghua Tang, Fei Fan, Xuefeng Cong, Lixing Zhao, Meiming Luo, Xiaoming Zeng,* Reductive Cross-Coupling between Unactivated C(aryl)–N and C(aryl)–O Bonds by Chromium Catalysis Using a Bipyridyl Ligand, J. Am. Chem. Soc. 2020142, 12834–12840.

11. Jinghua Tang,  Liu Leo Liu,  Shangru Yang,  Xuefeng Cong, Meiming Luo, Xiaoming Zeng,* Chemoselective Cross-Coupling between Two Different and Unactivated C(aryl)–O Bonds Enabled by Chromium Catalysis, J. Am. Chem. Soc. 2020, 142, 7715–7720. 

12. Zhi Rong, Meiming Luo,* Xiaoming Zeng,* Modular Arene Difunctionalization of Unactivated C−O and C−H Bonds by Sequential Chromium-Catalyzed Transformations, Org. Lett. 2019, 21, 6869−6873.

13. Liang Ling, Changpeng Chen, Meiming Luo,* Xiaoming Zeng,* Chromium-Catalyzed Activation of Acyl C−O Bonds with Magnesium for Amidation of Esters with Nitroarenes, Org. Lett. 2019, 21, 1912−1916.

14. Hong Meng, Sen Gao, Meiming Luo,* Xiaoming Zeng,* Iron and Phenol Co-Catalysis for Rapid Synthesis of Nitriles under Mild Conditions, Eur. J. Org. Chem. 2019, 4617−4623.

15. Xue Zhang, Liang Ling, Meiming Luo, Xiaoming Zeng,* Accessing Equatorially Difluoromethylated and Trifluoromethylated cis-Cycloalkanes and Saturated Heterocycles by Preferential Hydrogen-Addition to the Substitution Sites for Dearomatization, Angew. Chem. Int. Ed. 201958, 16785–16789.

16. Liang Ling, Yuan He, Xue Zhang, Meiming Luo, Xiaoming Zeng,* Hydrogenation of (Hetero)aryl Boronate Esters with a Cyclic (Alkyl)(amino)carbene–Rhodium Complex: Direct Access to cis-Substituted Borylated Cycloalkanes and Saturated Heterocycles, Angew. Chem. Int. Ed. 2019, 58, 6554–6558.

17. Yuan He, Jinghua Tang, Meiming Luo,* Xiaoming Zeng,* Regioselective and Chemoselective Reduction of Naphthols Using Hydrosilane in Methanol: Synthesis of the 5,6,7,8-Tetrahydronaphthol Core, Org. Lett. 2018, 20, 4159–4163.

18. Fei Fan, Jinghua Tang, Meiming Luo,* Xiaoming Zeng,* Chromium-Catalyzed Regioselective Kumada Arylative Cross-Coupling of C(aryl)–O Bonds with a Traceless Activation Strategy, J. Org. Chem. 2018, 83, 13549–13559.

19. Lei Jia, Qiang Tang, Meiming Luo,* Xiaoming Zeng,* One-Step Synthesis of Unsymmetric 1,1’-Biaryl-2,2'-diamines by the Reaction of 2-Naphthols with Aryl Hydrazines, Chin. J. Org. Chem. 2018, 38, 443–450.

20. Lei Jia, Qiang Tang, Meiming Luo,* Xiaoming Zeng,* Direct ortho-Selective Amination of 2-Naphthol and Its Analogues with Hydrazines, J. Org. Chem. 2018, 83, 5082–5091.

21. Changpeng Chen, Pei Liu, Meiming Luo, Xiaoming Zeng,* Kumada Arylation of Secondary Amides Enabled by Chromium Catalysis for Unsymmetric Ketone Synthesis under Mild Conditions, ACS Catal. 2018, 8, 5864–5868.

22. Xuefeng Cong, Fei Fan, Pengchen Ma, Meiming Luo, Hui Chen, Xiaoming Zeng,* Low-Valent, High-Spin Chromium-Catalyzed Cleavage of Aromatic Carbon−Nitrogen Bonds at Room Temperature: A Combined Experimental and Theoretical Study, J. Am. Chem. Soc. 2017, 139, 15182−15190.

23. Sen Gao, Liming Gao, Hong Meng, Meiming Luo,* Xiaoming Zeng,* Iron-Catalyzed Synthesis of Benzoxazoles by Oxidative Coupling/Cyclization of Phenol Derivatives with Benzoyl Aldehyde Oximes, Chem. Commun. 2017, 53, 98869889.

24. Jinghua Tang, Meiming Luo,* Xiaoming Zeng,* Chromium-Catalyzed, Regioselective Cross-Coupling of C–O Bonds by Using Organic Bromides as Reactants, Synlett 2017, 28, 2577–2580.

25. Weixi Zhang, Meiming Luo,* Iron-Catalyzed Synthesis of Arylsulfinates through Radical Coupling Reaction, Chem. Commun. 2016, 52, 2980−2983.

26. Lei Jia, Sen Gao, Junyao Xie, Meiming Luo,* Iron-Catalyzed Direct Alkylamination of Phenols with O-Benzoyl-N-alkylhydroxylamines under Mild Conditions, Adv. Synth. Catal. 2016, 358, 3840−3846.

27. Hong Qi, Tongxin Zhang, Kefeng Wan, Meiming Luo,* Catalytic Synthesis of 3-Thioindoles Using Bunte Salts as Sulfur Sources under Metal-Free Conditions, J. Org. Chem. 2016, 81, 4262−4268.

28. Weixi Zhang, Junyao Xie, Bin Rao, Meiming Luo,* Iron-catalyzed N-Arylsulfonamide Formation through Directly Using Nitroarenes as Nitrogen Sources, J. Org. Chem. 2015, 80, 3504−3511.

   ¨ Highlighted by Organic Chemistry Portal (http://www.organic-chemistry.org/abstracts/lit4/890.shtm).

29. Shuchao Wang, Fang Ren, Yuping Qiu, Meiming Luo,* Synthesis and Catalytic Activity of Nickel(II) Complexes of CNC Pincer-Type N-Heterocyclic Carbene Ligands, J. Organomet. Chem. 2015, 788, 27−32.

30. Si Chen, Lei Jia, Xiaonan Li, Meiming Luo,* Methyl Salicylate as a Selective Methylation Agent for the Esterification of Carboxylic Acids, Synthesis 2014, 46, 263–268.

   ¨ Highlighted by Organic Chemistry Portal (http://www.organic-chemistry.org/abstracts/lit4/344.shtm).

31. Zhijun Wei, Xuan Luo, Lin Zhang,* Meiming Luo,* POSS-Based Hybrid Porous Materials with Exceptional Hydrogen Uptake at Low Pressure, Micropor. Mesopor. Mat. 2014, 193, 35–39.

32. Pei Guo, Xiaoming Zeng, Si Chen, Meiming Luo,* Au(I)-N-Heterocyclic Carbene Complex-Catalyzed Synthesis of 1-Substituted Benzo[b][1,4]diazepines from N-Substituted o-Phenylenediamines and Terminal Alkynes, J. Organomet. Chem. 2014, 751, 438–442.

33. Tongxin Zhang, Weixi Zhang, Meiming Luo,* Metal-Free Reduction of Tertiary Phosphine Oxides with Hantzsch Ester, Chin. Chem. Lett. 2014, 25, 176–178.

34. Tongxin Zhang, Yan Zhang, Weixi Zhang, Meiming Luo,* A Convenient and General Reduction of Amides to Amines with Low-Valent Titanium, Adv. Synth. Catal. 2013, 355, 2775–2780.

35. Bin Rao, Weixi Zhang, Lan Hu, Meiming Luo,* Catalytic Desulfitative Homocoupling of Sodium Arylsulfinates in Water Using PdCl2 as the Recyclable Catalyst and O2 as the Terminal Oxidant, Green Chem. 2012, 14, 3436–3440.

36. Zhijun Wei, Hongbo Ren, Lin Zhang,* Meiming Luo,* Group IV M-POSS (MZr, Hf) Coordination Polymers, Chin. J. Chem. 2012, 30, 2591–2594.

37. Weixi Zhang, Xiaoqin Zhang, Meiming Luo,* Acyclic Palladium(II)-N-Heterocyclic Carbene Metallacrown Ether Complexes: Synthesis, Structure and Catalytic Activity, Chin. J. Chem. 2012, 30, 1423–1428.

38. Guanjun Cheng, Meiming Luo,* Homocoupling of Arylboronic Acids Catalyzed by CuCl in Air at Room Temperature, Eur. J. Org. Chem. 2011, 2519–2523.

39. Yan Zhang, Qiang Tang, Meiming Luo,* Reduction of Hydrazines to Amines with Aqueous Solution of Titanium(III) Trichloride, Org. Biomol. Chem., 2011, 9, 4977– 4982.

40. Yuancheng Qin, Hongbo Ren, Fanghua Zhu, Lin Zhang,* Chengwei Shang, Zhijun Wei, Meiming Luo,* Preparation of POSS-Based Organic–Inorganic Hybrid Mesoporous Materials Networks through Schiff Base Chemistry, Eur. Polym. J. 2011, 47, 853–860.

41. Guangming Nan, Fang Ren, Meiming Luo,* Suzuki-Miyaura Cross-Coupling Reaction of 1-Aryltriazenes with Arylboronic Acids Catalyzed by a Recyclable Polymer-Supported N-Heterocyclic Carbene-Palladium Complex Catalyst, Beilstein J. Org. Chem. 2010, 6, No. 70.

42. Yuancheng Qin, Yutie Bi, Hongbo Ren, Fanghua Zhu, Meiming Luo,* Lin Zhang,* Poly(methyl methacrylate)/Methacryl-POSS Nanocomposites with Excellent Thermal Properties, Chin. J. Chem. 2010, 28, 2527–2532

43. Xiaoqin Zhang, Yuping Qiu, Bin Rao, Meiming Luo,* Palladium(II)-N-Heterocyclic Carbene Metallacrown Ether Complexes: Synthesis, Structure, and Catalytic Activity in the Suzuki-Miyaura Reaction, Organometallics 2009, 28, 3093–3099.

44. Xiaoming Zeng, Tongxin Zhang, Yuancheng Qin, Zhijun Wei, Meiming Luo,* Synthesis of A Carbene Transfer Organometallic Polymer and Application to Forming a Recyclable Heterogeneous Catalyst for the Suzuki Reactions of Aryl Chlorides, Dalton Trans. 2009, 83418348.

45. Zhi Qiang Gao, Meiming Luo, Xiao Hua Sun, Hoi Lam Tam, Man Shing Wong*, Bao Xiu Mi, Ping Fang Xia, Kok Wai Cheah, and Chin Hsin Chen, New Host Containing Bipolar Carrier Transport Moiety for High-Efficiency Electrophosphorescence at Low Voltages, Adv. Mater. 2009, 21, 688–692.

46. Qiang Feng, Chao Zhang, Qiang Tang, Meiming Luo,* Synthesis of 1,10-Binaphthyl-2,20-diamine from 2-Naphthol under Atmospheric Pressure, Chin. Chem. Lett. 2009, 20, 1150–1152.

47. Qiang Tang, Chao Zhang, Meiming Luo,* A New Method for N-N Bond Cleavage of N,N-Disubstituted Hydrazines to Secondary Amines and Direct ortho Amination of Naphthol and Its Analogues, J. Am. Chem. Soc. 2008, 130, 5840–5841.

   ¨ Highlighted by Synfacts (2008, 7, 688).

48. Wei Wei, Yuancheng Qin, Meiming Luo,* Pingfang Xia, Man Shing Wong, Synthesis, Structure, and Catalytic Activity of Palladium(II) Complexes of New CNC Pincer-Type N-Heterocyclic Carbene Ligands, Organometallics 2008, 27, 2268–2272.

49. Yuancheng Qin, Wei Wei, Meiming Luo,* Suzuki-Miyaura Cross-Coupling Reaction of Arenediazonium Salts with Arylboronic Acids Catalyzed by a Recyclable Polymer-Supported N-Heterocyclic Carbene-Palladiun Catalyst, Synlett 2007, 2410–2414.

   ¨ Highlighted by Organic Chemistry Portal (http://www.organic-chemistry.org/abstracts/lit1/868.shtm).

50. Yingyong. Wang, Meiming Luo,* Qi Lin, Hua Chen, Xianjun Li, Efficient Biphasic Hydroaminomethylation of Long Chain Olefins in Ionic Liquids, Green Chem. 2006, 8, 545548.

51. Yingyong Wang, Junhua Chen, Meiming Luo,* Hua Chen, Xianjun Li, Highly Regioselective Hydroaminomethylation of Long Chain Alkenes Catalyzed by Rh-BISBIS in a Two-Phase System, Catal. Commun. 2006, 7, 979981.

52. Sujuan. Zhang, Xiaoming Zeng, Zhijun Wei, Dongbing Zhao, Tairan Kang, Weifeng Zhang, Mei Yan, Meiming Luo,* Desulfitative Suzuki Cross-Couplings of Arylsulfonyl Chlorides and Boronic Acids Catalyzed by a Recyclable Polymer-Supported N-Heterocyclic Carbene–Palladium Complex Catalyst, Synlett 2006, 18911894.

53. Chun Yan, Xiaoming Zeng, Weifeng Zhang, Meiming Luo,* Polymer-Supported N-Heterocyclic Carbene-Rhodium Complex Catalyst for the Addition of Arylboronic Acids to Aldehydes, J. Organomet. Chem. 2006, 691, 33913396.

54. Junhua Chen, X.iaoqin Zhang, Qiang Feng, Meiming Luo,* Novel Hexadentate Imidazolium Salts in the Rhodium-Catalyzed Addition of Arylboronic Acids to Aldehydes, J. Organomet. Chem. 2006, 691, 470474.

55. Tairan Kang, Qiang Feng, Meiming Luo,* An Active and Recyclable Polystyrene-Supported N-Heterocyclic Carbene-Palladium Catalyst for the Suzuki Reaction of Arylbromides with Arylboronic Acids under Mild Conditions, Synlett 2005, 23052308.

56. Yingyong Wang, Meiming Luo,* Yaozhong Li, Hua Chen, Xianjun Li, Progress in Hydroaminomethylation of Olefin, Chin. J. Org. Chem. 2005, 25, 11761181.

57. Yingyong Wang, Meiming Luo,* Yaozhong Li, Hua Chen, Xianjun Li, The Catalytic Hydroaminomethylation of Long Chain Alkenes with Dimethylamine in Aqueous-Organic Two-Phase System, Appl. Catal. A: General 2004, 272, 151155.

58. Yingyong Wang, Meiming Luo,* Yaozhong Li, Hua Chen, Xianjun Li, Hydroaminomethylation of 1-Dodecene Catalyzed by Water-Soluble Rhodium Complex, Chin. Chem. Lett. 2004, 15, 774776.

59. Meiming Luo,* Rugang Xie,* Pingfang Xia, Lin Tao, Deqi Yuan, Huaming Zhao, Catalytic Properties of Novel Cyclodextrin Dimers in the Hydrolytic Cleavage of p-Nitrophenyl Alkanoates, J. Phys. Org. Chem. 2001, 14, 515520.

60. Meiming Luo, Akiko Matsui, Tomoyuki Esumi, Yoshiharu Iwabuchi, Susumi Hatakeyama,* Concise Synthesis of Anolignan A, Tetrahedron Lett. 2000, 41, 44014402.

61. Meiming Luo, Yoshiharu Iwabuchi, Susumi Hatakeyama,* Regioselective Buta-1,3-dienylation of Aldehydes via Transmetallation of 2-Tributylstannylbuta-1,3-diene, Synlett 1999, 11091111.

62. Meiming Luo, Yoshiharu Iwabuchi, Susumi Hatakeyama,* Buta-2,3-dienylstannanes, Effective Reagents for Regioselective Buta-1,3-dienylation of Aldehydes and Acetals, Chem. Commun. 1999, 267–268.

授权专利

1. 罗美明,贾磊,谢君瑶,高森,一种N,N-二烷基胺基酚的制备方法,中国发明专利,授权时间2018.04.13,授权号ZL201610129737.2

2. 罗美明,齐鸿,一种3-吲哚硫醚的制备方法,中国发明专利,授权时间2018.02.06,授权号ZL201510978857.5

3. 罗美明,陈思,贾磊,李笑男,一种羧酸酯的制备方法,中国发明专利,授权时间2015.11.06,授权号ZL201310540820.7

4. 罗美明,张维熙,张彤鑫,一种非金属还原三级膦氧化物制备三级膦的方法,中国发明专利,授权时间2015.11.11,授权号ZL201310297714.9

5. 罗美明,张彤鑫,张维熙,一种还原酰胺类化合物的方法,中国发明专利,授权时间2015.02.18,授权号ZL201310343184.7

6. 罗美明,唐强,张衍,一种伯胺和仲胺类化合物的合成方法,中国发明专利,授权时间2012.12.05,授权号ZL200910060165.7

7. 秦元成,罗美明,祝华军,李明验梁隆,程志鹏,2-甲基哌嗪氟喹诺酮化合物及其制备方法和应用,中国发明专利,授权时间2013.11.06,授权号ZL200810147545.X

8. 张超,罗美明,祝华军,李明验梁隆,程志鹏,一种比阿培南的制备方法,中国发明专利,授权时间2012.08.08,授权号ZL200910001908.3

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